| Molecular Formula | C18H27NO2 |
| Molar Mass | 289.41 |
| Density | 1.029±0.06 g/cm3(Predicted) |
| Boling Point | 447.8±28.0 °C(Predicted) |
| JECFA Number | 2079 |
| Solubility | DMSO: >20mg/mL |
| Vapor Presure | 0-0Pa at 20-50℃ |
| Appearance | White to off-white powder. |
| Color | white to off-white |
| pKa | 14.18±0.70(Predicted) |
| Storage Condition | -20°C |
| Hazard Symbols | N - Dangerous for the environment![]() |
| Risk Codes | 50 - Very Toxic to aquatic organisms |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3077 9 / PGIII |
| FEMA | 4681 | (1R,2S,5R)-N-(4-METHOXYPHENYL)-5-METHYL-2-(1-METHYLETHYL)CYCLOHEXANECARBOXAMIDE |
| LogP | 3.95 at 22℃ and pH7.7 |
| Use | WS-12 has mint-like cool flavor, which can be used as oral care cool enhancer, chewing gum and sugar in children as a cooling agent. It can also be used as a cooling agent for skin and lipstick. |
| biological activity | WS-12 is an agonist of TRPM8 with an EC50 value of 39 nM. |
| Target | EC50: 39 nM (TRPM8) |